STATE OF BLOOD ACID-BASE BALANCE
IN THE SECOND AND THIRD TRIMESTERS OF UNCOMPLICATED PREGNANCY 

Panfilova Liliya Sergeevna, Postgraduate student, Samara State Medical University (16 Gagarina street, Samara, Russia), Liliya-panfilova@mail.ru  

618.2:616.152.11-07 

Background. The goal of the article is to study and analyze the parameters of the acid-base balance of blood in the second and third trimester of pregnancy without complications.
Materials and methods. The authors investigated arterial and venous blood of 80 patients with uncomplicated pregnancies and 32 non-pregnant women to determine the parameters of acid-base balance of blood by the «ABL5» gas analyzer of the Radiometer company (Denmark).
Results. It was found that the blood of women with physiological pregnancy accumulates acidic products of metabolism, reducing blood alkaline reserves – carbonate and protein buffers. The most significant oscillationsof the acid-base balance of blood were observed in the III trimester of pregnancy. But all of the observed changes were compensated due to the lack of the blood pH shift. 

pregnancy, acid-base balance of blood, laboratory diagnostics blood. 

1. Burlev V. A., Mamedalieva N. M., Sidel'nikova V. M. Akusherstvo i ginekologiya [Obstetrics and gynecology]. 1992, no. 2, pp. 19–20.
2. Litvitskiy P. F. Patofiziologiya: uchebnik [Pathophysiology: textbook]. Moscow: Geotar- Media, 2009, 496 p.
3. Tikidzhiev A. V. Klinicheskoe znachenie kislotno-osnovnogo sostoyaniya plodovoy krovi dlya techeniya i iskhodov rodov pri fetoplatsentarnoy nedostatochnosti: dis. kand. med. nauk [Clinical importance of acid-base balance of fetus blood for the course and outcome of labor in case of fetoplacental insufficiency: dissertation to apply for the degree of the candidate of medical sciences]. Moscow, 2008, 150 p.
4. Sabieva M. M. Kislotno-shchelochnoe ravnovesie krovi u zhenshchin pri beremennosti: dis. kand. med. nauk [Acid-base balance of blood in pregnant women: dissertation to apply for the degree of the candidate of medical sciences]. Moscow, 1969, 191 p.
5. Savel'eva G. M. Akusherstvo [Obstetrics]. Moscow: Meditsina, 2000, 816 p.